液相色谱质谱联用仪
仪器介绍
SCIEX 7500+ 系统是一款尖端的三重四极杆质谱仪，专为在复杂基质中长期保持卓越灵敏度而设计。该先进系统显著提升了定量精度，使得在延长时间和大规模样本集中获得准确结果成为可能。借助 SCIEX 7500+，研究过程变得更加高效，从而增强了应对新兴分析挑战的信心。SCIEX 7500+ 针对大规模多重反应监测（MRM）进行了优化，并具备增强的前端用户可维护性，能够有效管理仪器的停机时间。此项突破性技术在多个应用领域中实现了超灵敏的定量分析，包括药物开发、新兴污染物检测和生命科学研究。SCIEX 7500+ 的性能经过严格的测试，针对已知可能引发仪器污染的基质进行了加速高通量检测。结果表明，该系统能够提供灵敏且可靠的定量能力，确保在复杂基质中准确测量超低浓度化合物，同时显著降低停机风险。
参数
| Core ExionLC AE System | |
| Pump | Ultra-High Pressure Binary Gradient Pump |
| Flow rate | 0.010 mL/min - 5.000 mL/min |
| Flow rate precision | < 0.075% RSD |
| Pressure range | ≥ 15,000 psi |
| Column oven | Ambient temperature - 85°C |
| Sample tray | Accommodates over 160 positions, compatible with 1.5 mL or 2 mL sample vials. |
| Injection volume | 0.1 - 50 µL |
| Sampler temperature range | Equipped with cooling function, temperature control from 4°C to 40°C. |
| SCIEX 7500+ | |
| Scan range | Low mass≥5 amu, high mass≤2000 amu |
| Mass accuracy | ≤ 0.1amu/24 hr |
| Dynamic range | ≥ 6 order |
| Resolution | ≥ 9000 |
| Positive and negative polarity switching time | ≤ 5 ms |
| MRM dwell time | ≥ 0.5 ms |
| MRM acquisition speed | 800 MRM/s |
| Sensitivity | •ESI+ sensitivity: 1 pg reserpine directly injected, MRM ion pairs m/z 609 and 195, resolution set to 0.6-0.8 amu (FWHH), signal-to-noise ratio ≥ 3,000,000:1. •ESI- sensitivity: 1 pg chloramphenicol directly injected, MRM ion pairs m/z 321 and 152, resolution set to 0.6-0.8 amu (FWHH), signal-to-noise ratio ≥ 3,000,000:1. |
| Scan mode | Including but not limited to full scan, product ion scan, precursor ion scan, neutral loss scan, multiple reaction monitoring (MRM) scan, automatic MS/MS scan, selective ion monitoring, time programming, positive/negative polarity switching, and MRM3 scanning mode. |