液相色谱质谱联用仪
仪器介绍
Orbitrap Exploris 480质谱仪是革命性的新一代模块化超高分辨率质谱仪，它占用的空间更小，同时保持高分辨率、高质量的精度和图像质量。它结合了成熟的技术、先进的功能和智能驱动的分析框架，使科学家能够更广泛地使用质谱进行高通量蛋白质鉴定、定量和结构表征。Vanquish Flex采用先进的等压四元或高压二元溶剂混合技术，最大限度地提高分离灵活性、样品处理精度、分离控制可靠性，并扩大分析物的检测范围。Vanquish™Neo UHPLC系统为致力取得科学新突破的研究人员提供了全天候 (24/7) 卓越性能的纳流、毛细管流和微流 LC-MS。从组学和生物制药到高通量转化研究，Vanquish Neo UHPLC系统是低流LC 的新标准。
参数
| Scan rate | Up to 40 Hz at resolution setting 7500 at m/z 200 Multiplexity: up to 20 precursors/scan |
| Resolution | Up to 480,000 at m/z200 |
| Mass accuracy | < 3 ppm RMS drift over 24 hours using external calibratior < 1 ppm RMS drift over 24 hours using internal calibration |
| Sensitivity | Dynamic range > 5000 within a single Orbitrap mass analyzer spectrum MS/MS: 50 fg reserpine on column S/N 100:1 SlM: 50 fg reserpine on column S/N 150:1 |
| Features | Higher Energy Collisional Dissociation (HCD) EASY-ICTM (internal calibration) source Quadrupole mass flter lon Routing Multipole (lRM) trapping, focuses and routes ions more effectively Orbitrap mass analyzer Broader range of experiments with multiple scan modes: data-dependent acquisition (DDA), data independent acquisition (DlA), spectral multiplexing (lMSx, TopN and new TopSpeed (TopS), BoxCar DlA and DDA experiments, tSlM, tSlM MSx, ddMS/MS, targeted MS/MS |
手册
Orbitrap Exploris 480_Brochure_EN