200
Internal Users
10
External Users
150
Services Offered
300
People Trained Per Year
We now have ten cores, featuring over 60 instruments.
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Genomics
The Genomics Core specializes in the rapidly evolving fields of genomics, including single cell multi-omics, spatial transcriptomics, metagenomics, and epigenomics, among others. Leveraging cutting-edge genome technologies, innovative analytical methods, and a dedicated team of experts, the Core provides researchers with equal access to a diverse array of professional genomic research tools. Our state-of-the-art facility includes advanced sequencing platforms, single cell spatial imaging systems, and bioinformatics resources that enable detailed and comprehensive genetic analysis. Additionally, the...
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Proteomics and Metabolomics
The Proteomics and Metabolomics Core focuses on providing solutions for the entire process of proteomics and metabolomics based on liquid chromatography-mass spectrometry technology to support life science research. The Core is outfitted with several top-of-the-line mass spectrometers, such as Thermo Scientific Orbitrap Exploris 480, Bruker timsTOF HT, and Bruker rapifleX MALDI-TOF/TOF, which can meet the diverse needs of on-campus and off-campus users for qualitative proteomics, quantitative proteomics, post-translational modification proteomics, targeted/untargeted metabolomics, lipidomics, and mass...
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Brain and Cognitive Sciences
The Brain and Cognitive Sciences Core at BioCRF is committed to delivering state-of-the-art neuroscience research tools for in-depth, cross-disciplinary exploration of brain functions and disorders. The Core boasts an array of cognitive behavioral instruments and non-invasive neuroimaging technologies, including desktop and portable electroencephalography (EEG), polysomnography (PSG), functional near-infrared spectroscopy (fNIRS), and eye tracker. Specialized labs are also established that merge stringent experimental precision with environmental comfort. Additionally, the Core features cutting-edge electrophysiological equipment, such as...
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Imaging
The Imaging Core at BioCRF is a leading facility that offers access to various forefront imaging equipment and cutting-edge analysis tools for researchers. The Core comprehensively integrates diversified optical imaging technologies, including wide-field imaging, total internal reflection fluorescence imaging, confocal microscopy, spinning disk confocal, high-content screener, light sheet, two-photon, slide scanner, atomic force microscopy, live cell imaging, and super-resolution imaging. Additionally, the Core provides professional image processing workstations and image analysis software, empowering researchers to...
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Flow Cytometry and Cell Culture
The Flow Cytometry and Cell Culture Core at BioCRF is a comprehensive service platform that provides cell function analysis. The Core is equipped with flow cytometers, 3D bioprinter, electroporation system, microelectrode array system and essential cell culture facilities such as class II biosafety cabinets, incubators, centrifuges, refrigerators/freezers, basic microscopes and automated cell counters. In addition to access to state-of-the-art instrumentation, the Core also offers professional technical support, theoretical and technical training, cell line resources and...
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Histology
The Histology Core focuses on providing first-class histology technology and consulting services for researchers, aiming to assist them in conducting preclinical studies in various disciplines. The Core provides access to equipment such as cryostat, microtome, paraffin-embedding station, vibratome, and autostainer, combined with high-throughput scanner in the Imaging Core, enabling fast and high-quality analysis of stained tissues. The Core works closely with researchers, providing professional tissue sample processing service, to offer strong support for their research....
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Synthetic Biology
The Synthetic Biology Core at BioCRF is furnished with a biofoundry, featuring automation and analytics infrastructure to aid in the engineering of biological systems. The biofoundry includes robotic liquid-handling equipment, high-throughput analytical tools, necessary software, and data management systems to operate the equipment and support broader biofoundry capabilities. In addition, the Core is equipped with advanced tools such as QPix 420, ARTP, and the Microbial Microdroplet Culture system, providing necessary support for the development and...
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High Throughput Screening
The High Throughput Screening Core at BioCRF is a pivotal resource that offers infrastructure and specialized expertise to support research investigators in the identification and exploration of new compounds or tool molecules for basic research and pharmacological discovery. The Core is fully equipped with a wide range of resources, including diverse small molecule libraries, advanced cell culture facilities, and a full suite of automated systems for detection, robotics, imaging, and verification, tailored for work in...
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Structural Biology
The Structural Biology Core at BioCRF is a valuable resource for researchers seeking to delve into the intricate molecular structures, which is equipped with a range of advanced instruments, including the Dragonfly liquid handler, nanolitre liquid handler, Jansi UVEX imaging system, Vitrobot for Cryo-EM sample preparation, and chameleon for automated Cryo-EM sample preparation. The Core is dedicated to providing state-of-the-art equipment and expert consultation to support researchers. The Structural Biology Core works in synergy with...
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General Equipment
The General Equipment Core at BioCRF is committed to providing comprehensive general research infrastructure for researchers on and off campus. The shared equipment includes a wide range of resources such as various models of centrifuges, microplate reader, nanoparticle tracking system, seahorse cell metabolic analyzer, Typhoon biomolecular imager, ChemiDoc imaging systems, nanoparticle size and zeta potential analyzer, and gradient preparation and separation systems. In addition, abundant training resources and technical support is available to enable our...
