GC-MS System
Equipment Introduction
Gas chromatography (GC) is a chromatographic technique suitable for separating and analyzing volatile, semi-volatile, and thermally stable compounds. The Agilent 8890/5977C GC/MSD system is a high-performance gas chromatography-single quadrupole mass spectrometry system. Its core electronic pressure control (EPC) technology ensures excellent pressure and flow accuracy across the entire system, laying the foundation for method reproducibility and reliability. The capillary flow technology (CFT) not only enables precise flow splitting but also supports advanced applications such as detector splitting, column backflushing, and multidimensional chromatography. For instance, it can be optionally configured to simultaneously direct chromatographic effluent to both a mass spectrometric detector (MSD, for qualitative identification) and a flame ionization detector (FID, for high-accuracy quantification), thereby comprehensively enhancing analytical capabilities through complementary multi-source data. GC-MS technology is widely used in environmental monitoring, food safety, petrochemical analysis, and forensic science, among other fields. It serves as a workhorse for routine targeted analysis in various laboratories, renowned for its reliability and efficiency.
Specification
| 8890 GC System | |
| Column oven | a) Operating temperature: 4°C to 450°C above room temperature. b) Temperature setting: Step size 1°C, program heating interval 0.1°C. c) Heating rate: programmable heating, 120°C /min; Programmable cooling, can be reduced from 400°C to 50°C within 4 minutes. d) Program heating: 20 stages, 21 temperature platforms. e) Stability: ≤ 0.01°C /1°C (with a variation range of 0.01°C for every 1°C). f) Column replacement without venting. |
| Split/non split injection port | a) The maximum temperature is 400°C. b) Pressure range: 0-100 psi, electronic pressure control accuracy: 0.001 psi |
| GC-FID | a) Electronic pressure/flow control (electronic pressure control). b) Equipped with automatic shutdown detection function. c) Sampling rate of 1000 Hz. d) Minimum detection limit: ≤ 1.2 pg carbon/second |
| Liquid autosampler | a) Number of positions for sample vials (2 mL-vial): 50 positions, 3 self-cleaning positions. b) Injection volume range: between 0.1-10 µL |
| Mass Resolution | Linear mode ≥ 1,200 for Cytochrome C (m/z 12,361) FWHM； Reflect mode ≥ 50,000 for Somatostatin 28 (m/z 3,147.5) FWHM; MS/MS Fragment Resolution，≥ 1,500 for [Glu1]-Fib fragment m/z 175, ≥ 5,000 for [Glu1]-Fib fragment m/z 684, ≥ 7,500 for [Glu1]-Fib fragment m/z 1,056, ≥ 10,000 for [Glu1]-Fib fragment m/z 1,441 |
| MS Sensitivity | Linear mode, 500 fmol BSA (m/z 66,000) at S/N ≥ 100:1 shown with 1,000 laser shots；Reflect mode , 250 amol [Glu1]-Fibrinopeptide B (m/z 1,570.7) at S/N ≥ 200:1 shown with 2,000 laser shots; MS/MS mode: 250 amol [Glu1]-Fibrinopeptide B fragment 1,056 Da at S/N ≥ 30:1 shown with 1,000 laser shots |
| 5977C MSD System | |
| EI source | Ionization energy 5-241.5 eV |
| Ion source temperature | 350°C |
| Quadrupole mass analyzer | a) A quartz gold-plated conjugate hyperbolic quadrupole b) Independent temperature control c) Temperature control range: 106-200°C d) Maintenance free for life |
| Signal-to-noise ratio | EI full scan ≥ 5000:1 s/n (1pg OFN, scanning range 50-300 amu) |
| Scanning speed | up to 20000 amu/s |
| Mass range | 0.6~1091 Da |
| Mass stability | <0.10 amu/48h |
| Dynamic range | ≥ 106 |
Brochure
Agilent 8890/5977C GC/MSD_Brochure_EN