Analysis and Purification LC
Equipment Introduction
Vanquish Analytical Purification LC Systems is the fully integrated, high-performance Thermo Scientific Vanquish Fraction Collector (VFC), which allows you to achieve pinpoint purification by fractionation with precision. The Vanquish Analytical Purification LC Systems support a broad range of applications for both upstream (e.g., raw materials and synthetic products) and downstream processes (e.g., protein purification, oligonucleotide synthesis). They match the separation power of the LC systems with compelling fractionation for high-purity and high-yield compound collection. Built with Thermo Scientific Vanquish HPLC and UHPLC system components, they deliver unrivaled performance, robustness, and user-friendliness.
Specification
| System pressure, maximum | 1000 bar |
| Flow range, maximum | 0–8 mL/min |
| Pump options (default gradient delay volume) | Quaternary (679 µL) |
| pH range | 2–12, chloride concentration up to 1 mol/L |
| Split sampler FT | • Max. 1500bar (22,000psi) • Out-of-the-box vial capacity of 216 samples • Utilize air stream cooling to maintain sample integrity • Automated sample configuration using barcode reading |
| Column compartment H | • Temperature Range : column chamber: 5–120 °C; pre-heater: 40–120 °C ; post-column cooler: 40–80 °C • Capacity: 2 column slots • Pressure Range: 5–151 MPa, (50–1517 bar, 700–22,000 psi) |
| Integral fraction collector FT | • Sample capacity: the following sample racks or well plates with SBS footprint format: 54 × 12 mm O.D. vials (≤1.5 mL); 9 × 22.5 mm O.D. vials (≤10 mL); 96- and 384-position well plates (deep and shallow) • Collection modes: Triggered by peak signals or time frames; (Saw)vertical, (saw)horizontal; Interrupt and continuous collection modes; Collect above or inside vessel; Manual collection, pooling, wrapping and concatenating • Delay volume: <19 µL • Fraction valve: Low internal volume: <0.5 µL; Fast switching time ~30 ms; Maximum operating pressure: 138 bar (2000 psi) • Min. collection volume: One droplet collection volume: ≥6 µL (water) • Operating flow rate: 0.05–10 mL/min • Temperature range 4–40 °C, cooling ≥23 K below ambient at <80% relative humidity |
Brochure
Vanquish Analytical Purification LC Systems_Brochure_EN