LC-MS
Equipment Introduction
The Orbitrap Exploris 480 mass spectrometer is a revolutionary new generation of modular ultra high-resolution mass spectrometry (ums) that takes up less space while maintaining high-resolution, high-quality accuracy and image quality. It combines mature technologies, advanced functions, and an intelligent driven analytical framework for the wider use of mass spectrometry by research scientists for high-throughput protein identification, quantitative and structural characterization. Vanquish Flex utilizes advanced equal pressure quaternary or high-pressure binary solvent mixing technology to maximize separation flexibility, improve sample processing accuracy, improve separation control reliability, and expand the detection range of analytes. Vanquish™ Neo UHPLC system delivers maximum performance 24/7 for nano-, capillary-, and micro-flow LC-MS. From -omics and biopharma to high-throughput translational research, the Vanquish Neo UHPLC system is the new standard in low-flow LC.
Specification
| Scan rate | Up to 40 Hz at resolution setting 7500 at m/z 200 Multiplexity: up to 20 precursors/scan |
| Resolution | Up to 480,000 at m/z200 |
| Mass accuracy | < 3 ppm RMS drift over 24 hours using external calibratior < 1 ppm RMS drift over 24 hours using internal calibration |
| Sensitivity | Dynamic range > 5000 within a single Orbitrap mass analyzer spectrum MS/MS: 50 fg reserpine on column S/N 100:1 SlM: 50 fg reserpine on column S/N 150:1 |
| Features | Higher Energy Collisional Dissociation (HCD) EASY-ICTM (internal calibration) source Quadrupole mass flter lon Routing Multipole (lRM) trapping, focuses and routes ions more effectively Orbitrap mass analyzer Broader range of experiments with multiple scan modes: data-dependent acquisition (DDA), data independent acquisition (DlA), spectral multiplexing (lMSx, TopN and new TopSpeed (TopS), BoxCar DlA and DDA experiments, tSlM, tSlM MSx, ddMS/MS, targeted MS/MS |
Brochure
Orbitrap Exploris 480_Brochure_EN